Top Factors affecting IVF Success and Failure

IVF (in-vitro fertilization)is an assisted reproductive technology that aids in fertilization, embryo development, and implantation. It is one of the most effective types of reproductive technology. IVF works by combining medications and surgical procedures to help fertilize an egg, and the fertilized egg is implanted in your uterus. 

In Vitro Fertilization (IVF) is a complex process that relies heavily on expertise, timing and accuracy. There are numerous factors that influence the chances of success and failure of infertility treatments and the same holds true in case of IVF procedures. 

Here are the Top Factors affecting IVF Success and Failure

  1. Previous Pregnancy

Successful pregnancy in the past can be a factor that will lead to better chances of a successful pregnancy by the IVF procedure. On the other hand, women who have had recurrent miscarriages may have difficulty conceiving using IVF. Advanced ART techniques such as PGT and ERA may be useful in such cases.

  1. Age

The age of the woman plays an important role in the success of treatment. Women have the best chances of success with IVF treatment between the ages of 24 and 34 because this is when women are most fertile. The success rate decreases as one gets older. This is because the quality and/or quantity of a woman’s eggs decreases as she ages.

  1. Egg and Embryo Quality

Some of the other items on this list, such as age, ovarian reserve, stimulation protocol, and sperm quality, affect the quality of eggs and embryos. The higher the quality of the eggs and embryos, the more likely the IVF procedure will be successful.

  1. Controlled Ovarian Stimulation (COH) Protocol

It describes the various types of fertility medications, as well as how they are administered and when they are given. The primary goal is to produce a large number of mature oocytes so that at least one egg can cause pregnancy. 

  1. Implantation Issues

        Implantation issues happen when an embryo fails to implant in the uterus. Implantation issues happen because of various reasons, such as the presence of uterine polyps, a premature increase in progesterone levels, an endometrial lining that is too thin, or an infection of the uterus.

  1. Sperm Quality

Approximately 90% of chromosomal embryo problems are caused by poor egg quality. However, male fertility factors continue to have an impact on embryos. If the male partner has fertility issues, new technology is helping to mitigate the negative effects and increase the likelihood of a successful pregnancy.

  1. Fertility Problem

Endometriosis, blocked fallopian tubes, PCOS, and, in men, low sperm count, motility, and morphology are all issues that can usually be easily treated with IVF, on the other hand, issues like fibroids, uterine abnormalities, and ovarian dysfunction are more difficult to treat with simple IVF and require other surgeries or donor programs.

  1. Uterine Receptivity

Uterine Receptivity is a complicated process in which embryos attach, invade and develop into a new individual. This is just as critical as embryo quality. Similar to planting a seed, if the quality of the seed or soil is compromised, the chances of growing a healthy plant are reduced. The thickness of the uterine lining, immunological factors, and the contour of the uterine cavity are all factors that influence receptivity.

  1. Donor gametes-

For IVF to work, the fertility clinic needs both healthy eggs and sperm. Patients whose egg quality is at risk due to age or other factors can go for the egg donor. For those who are unable to use their own eggs, egg donor IVF is an option. Couples that struggle with male factor infertility can also use donor sperm. Common reasons include reproductive organ damage, hormonal issues, genetic defects, or diseases. Sperm and Egg donor IVF success rates are high, higher than the average IVF success rates for couples who do not use a donor. 

10.    Lifestyle

A healthy lifestyle will foster a thriving environment for an embryo. Stop smoking and drinking alcohol at least three months before starting IVF. Smoking and drinking reduce the chances of having success in the procedure. The chances of implantation are 50% lower in smokers than in nonsmokers. Maintaining a healthy weight is also essential for improving IVF success rates.

Ferticare helps people with natural conception, IVF, IUI, Donor Sperm, Donor Egg, and Surrogacy. We offer customized and budget-friendly treatment plans and connect patients with the right doctor based on their requirements. If you are struggling to conceive, you can schedule a free consultation with our counselor

Author: Dr. Mangala Devi.

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